Urea is a cool lad because it’s both a keratolytic and hydrating agent. glycerides citrate 62 patients with pityrosporum folliculitis were given either ketoconazole (oral and topical; 200 mg and 2% shampoo daily), ketoconazole (oral only; 200 mg daily), econazole nitrate 1%, or miconazole nitrate 2% cream. You will learn a lot, and I’ve tried to answer every possible question you might have. Did the trick, but destroyed my stomach whilst taking it, and after a couple months off of it, the millions of teeny bumps came back with a vengeance. It stops fungus from accumulating squalene by disrupting fungal sterol biosynthesis. (145). When taken orally, it’s delivered into the stratum corneum, nails, and hair through sebum. Not only that, one study found neem extract wasn’t very effective against malassezia. I’ll see you on the other side! Not only can they look similar to the untrained eye, but it's very common for someone to have both forms of acne at once, sometimes even in the same area. Gonna be honest: It's pretty difficult to tell the difference between fungal acne and regular ol' acne (aka acne vulgaris, aka closed comedones, aka clogged pores, aka whiteheads). Not to mention, we have enzymes on the skin called ceramidases that break down ceramides into its respective parts (free sphingosines and fatty acids), which can then be utilized by malassezia. There are plenty of good products out there without petrolatum. It contains triglycerides, fatty acids, wax esters, sterol esters, cholesterol, cholesterol esters, and squalene. Check out this graph to see what I mean. Also, while Differin, like retinoids in general, is pretty lackluster as a monotherapy, it enhances the effectiveness of an ingredient used in combination with it. They did this for 3 consecutive days, with subsequent treatment once a week. Firstly, cholesterol was only ever able to induce mycelium when combined with other esters that would yield problematic fatty acids. Here’s a quote directly from him: “Discovering azelaic acid was a breakthrough for me…. PEG-40 stearate Fun fact #5: my sister cured her hormonal adult acne with sulfur. (129), “A significant feature of CPO is that no single case of fungal resistance has been reported so far, even though it was introduced into clinical therapy more than three decades ago…. It has an MIC range of 0.003-4 microg/mL. I’m sure I’ll have plenty of comments further down the line as I continue to absorb this, but I have to say it’s quite revelatory, even for someone like me who has done his reading regarding Malassezia-induced conditions. Because antibiotics and antibacterial products can disrupt the balance of fungus and bacteria on your skin, making Malassezia folliculitis worse. Eucerin DermatoClean Refreshing Cleansing, Benton Honest TT Mist (contains tea tree). Pair that with the fact that malassezia varies tremendously depending on geographical location and…. Fun fact #6: urea has been used to treat various skin diseases for over a century. (6, 7, 8). glyceryl caprylate] inhibit the fungal growth in a dose-dependent manner. (188) To summarize: Unfortunately, many products with Azelaic Acid contain problematic ingredients like esters and polysorbates. In my experience, azelaic acid treats inflammatory acne better than non-inflammatory acne (whiteheads and blackheads). Welcome to JACQ's, The Most Interesting Vegan, Sustainable and Organic Skincare For Women of Color By Women of Color. Thus, the AA/Mino combination can be regarded as valuable therapeutic alternative in patients for whom isotretinoin is not indicated, who do not wish to use or cannot tolerate tretinoin therapy. As far as I’m aware the other malassezia isolates have yet to be tested. Recall how malassezia feeds on 11-24 carbon chain fatty acids. (137) But don’t worry, this doesn’t mean it’s a bad thing. If you want to be SUPER cautious, remove it altogether. Source: The Role of Sebaceous Gland Activity and Scalp Microfloral Metabolism in the Etiology of Seborrheic Dermatitis and Dandruff. Hydroxypyridones (ciclopirox) = synthetic anti-fungals that also possesses antibacterial and anti-nflammatory properties. In one study, thirty patients with chronic seborrheic dermatitis were asked to apply a mixture of 90% raw honey and 10% water on affected areas for 3 hours every other day. Now that we’ve gone over what to avoid with malassezia, let’s discuss how to TREAT it. The 7 patients who used oral itraconazole saw improvement after 14 to 18 days. (114). This study found that glycerin was actually an EFFECTIVE TREATMENT for malassezia folliculitis. Water, Cyclopentasiloxane, Polypropysilsequioxane, Isododecane, Dimethicone, C30-45 Alkyldimethylsilyl, Polypropylsilsequioxane Silica, Glycerin, Peg-10 Dimethicone, Dimethicone/Polyglycerinej-3 Crosspolymer, Sodium Chloride, Nylon-12, Paraffin, Cyclomethione, Aluminum Hydroxide, Disodium Edta, Disodium Stearoyl Glutamate, Dipropylene Glycol, Disteardimonium Hectorite, Acrylates Copolymer, Phenoxyethanol Chlorphenesin, Ethylparaben, [+/- May Contain CI 77007 / Ultramarines, CI 77491, CI 77492, CI 77499 / Iron Oxides, CI 77891 / Titanium Dioxide]. Make sense? glycerin + fatty acid = glyceride, also known as a glycerol ester. I hope you’ve learned something new, and I wish you the best of luck on your skincare journey with malassezia. https://www.target.com/p/cerave-ultra-light-moisturizing-face-lotion-with-sunscreen-spf-30-1-7oz/-/A-52723364. However, I recommend you stick to lower pH things like chemical exfoliants because alkaline substances (e.g. Not seen in the chart above, but equally important: avoid fermented products, specifically GALACTOMYCES. As of right now, I don’t know how it is affecting my skin since I just switched a lot of products (skincare and makeup). do you think it is safe for fungal acne? Oral itraconazole (200mg daily for 1 week), ketoconazole (400mg single dose, repeated in 1 week) and fluconazole (Diflucan®) (150mg-300mg weekly for 1 month) have been shown to be effective. I had 2 things under sever- chlorine and fluoride. I recommend choosing things that DO NOT have any asterisks when first starting off. 5 Black-Owned SPFs You'll Want to Shop Immediately, I Tried CoolSculpting My Chin and I Have Thoughts, You Need to Try These Natural Sunscreens ASAP, The *Only* Fix I've Found for My Bumpy Arms. Sunscreen — Elta MD SPF 46 Sunscreen PM Routine 1. (81, 82) So basically…. Thank you for being considerate. Other esters that in vitro studies have shown malassezia can metabolize: Note: polyethylene glycol monostearate was not metabolized by M. obtusa, M. globosa, M. restrica but was by  M. furfur, M. sympodialis, M. slooffiae. You can still make recommendations for me over at that page! Different species can cause different skin problems, which leads to our next section…. Best Products for Pityrosporum Folliculitis. I got that CARBON 8 chain length!” Then malassezia starves to death. The ones that appear most in skincare products are even numbered. baking soda) are bad for skin health. • What you should be alert for in the history Pityrosporum folliculitis is a condition in which the hair follicles of the sebaceous areas (upper trunk, shoulders, and occasionally head and neck) are infected with Pityrosporum (Malassezia) yeasts, resulting clinically in inflammatory papules and pustules. I am in Europe, but can easily order on amazon or the like if need be. Unfortunately, malassezia is quite the practical fella and has enzymes (lipases and phospholipases) that can hydrolyze triglycerides into free fatty acids. I know I mentioned earlier that squalene can cause malassezia to proliferate, but this is not the case for the skincare derived version (squalane). u/svvaffles also recently shared her before and after photos on r/skincareaddiction, and regularly uses squalane in her routine! The pathology of malassezia is very complicated, and varies tremendously according to geographical location and ethnicity. Particularly, the lack of teratogenicity makes therapy with 20% AA cream plus oral minocycline an optimal alternative to isotretioin therapy in women of childbearing potential.”. This is something I just discovered and will try in the future! One of the most common amino acids you’ll see in skincare products is arginine. Just try to make healthier food choices and avoid prolonged use of broad spectrum antibiotics if they aren’t necessary. ethyl octanoate [carbon chain length 8] can reverse the growth promoting effects [of malassezia] by generating a selective activation of antimicrobial activity esp. I chose products that you recommended from the post about Mal. PEG-Glyceryl Stearate As of today I will no longer be approving comments on this blog post asking me to vet products. trihydroxystearin rubbing alcohol) and you get isopropyl palmitate — a common ingredient in many moisturizers like the popular Aveeno Daily Moisturizing Lotion. Here’s a quote: “Most commercially available antifungal products contain esters or medium / long chain free fatty acids. (9) Or more simply put, it grows in the presence of human skin oil. -_-, Unfortunately malassezia feeds on fatty acids with carbon chain lengths 11-24. Feel free to recommend something to add to this constantly growing list. It breaks it down into sever, moderate and mild. It’s frequently misdiagnosed as “normal” acne, which is extremely frustrating because this often leads to unnecessary and prolonged treatment with medications like antibiotics that only further exacerbate the condition. Avobenzone (3%), Homosalate (10%), Octisalate (5%), Octocrylene (2.7%). I have found no evidence that the same applies to saccharomyces, a different but similar genus of fungi. Cleanser — Avene Tolerance Extreme Cleansing Lotion (no rinse, I only use cotton pad to remove lotion) 3. Pityrosporum folliculitis, also known as Malassezia folliculitis, is a condition that presents as breakouts on your skin. From one couch potato to another, yuh gotta EXERCISE! There are exceptions, but it’s a good rule of thumb. How to Tell if You Have it. (142) It’s obtained from cinnamon oil, balsams such as storax, or shea butter. Three asterisks (***) = has both esters and fatty alcohols. This is one of the only antifungals I have not tried, but it’s another option. Moisturizing Toner (?) An anti-fungal and keratolytic agent. However, that being said, I still have so many unanswered questions and curiosities that I am dying to know. A case study of a woman who cleared her fungal acne by slathering a thick layer of ciclodan cream (0.77%  ciclopirox olamine) every night. I’ve seen a few people throw around the idea of using coconut oil because it is an “anti-fungal.” DO NOT DO THIS. “More precisely, they identified glycolipid and glucosylceramide as the first small molecules synthesized by C. albicans that are specifically required for virulence.” (168). *PLEASE LET ME KNOW IF ANYTHING IS IN THE WRONG ORDER! Another tale-tell sign is if you breakout out from literally EVERYTHING. Folliculitis and they mentioned Nizoral Dandruff Shampoo for the face. Studies have shown that it wipes out bacteria and fungi and never creates a resistance. Not everything is glycerin-free, of course – but you’ll see them again on this list! You see a doctor. Dr. Kim says for milder cases, something as simple as dandruff shampoo can help, since dandruff products contain yeast-killing ingredients like zinc pyrithione or selenium sulfide. The main results included reduction of the scaling and erythema. octyldodecanol), I recommend avoiding them altogether if you’re still struggling with malassezia.
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